What should I do if my dosage changes while my TUE is still valid?

If the type of medication and/or dosage changes before your TUE expires, you must contact the CCES to request a new TUE, because a TUE is only valid for the specific substance(s), dosage, route of administration, frequency, and duration. If you have been issued a TUE by the CCES, the letter of approval will highlight what elements should be submitted in the event your medication and/or dosage changes.